Abstract: To evaluate the safety of Panax notoginsengas medicinal materials and provide theoretical basis for the control of soil heavy metal pollution, the contents of eight heavy metals in tillage layer soil (0-20 cm), subsoil layer (>20-40 cm) and P. notoginseng in the main planting fields of Yunnan Province were analyzed. Inductively coupled plasma mass spectrometry (ICP-MS) was used to determine the contents of heavy metals. Soil heavy metal pollution was assessed by single pollution index (P_i), Nemerow integrated pollution index (NIPI) and potential ecological risk index (PERI). Estimated daily intake (EDI), target hazard quotient (THQ) and hazard index (HI) were used to estimate the risk of intake of parts of plants on human. Bioconcentration factor (BCF) and transport factor (TF) were used to evaluate the enrichment and transport capacity of heavy metals in plants. The results show that the pollution degree of heavy metals in P. notoginseng planting soil is in the order of Cd>Cu>Cr>Ni>Pb>As>Hg>Zn; The planting soil of P. notoginseng is moderately contaminated by heavy metals and has moderate ecological risk; The contents of heavy metals exceeded the standard for all five parts of P. notoginseng, including taproots, fibrous roots, rhizomes, stems and leaves. Especially Hg in the shoots excessively exceeds the standard. However, none of them pose any human health risk; The enrichment coefficients of heavy metals in all parts of plants are less than 1. Specifically, the enrichment capability of Cd is the strongest and Pb is the weakest in taproots, fibrous roots, rhizomes and stems. The enrichment capability of Hg is the strongest and Cr is the weakest in leaves; The transport capacity of heavy metals in plants is in the order of Hg>Cu>As>Zn>Pb>Cd>Ni>Cr.