Abstract: The improvement of pollutant oxidation degradation efficiency by adding natural organic catalysts has attached widespread attention in recent years. Studies have shown that organic compounds can accelerate the process of classical oxidation reactions by promoting the reduction of transition metals or complexing transition metals, and can also activate oxidants directly to generate oxidative free radicals. Based on the promotion of typical organic functional groups on the chemical oxidative process, metal-organic framework has been developed and applied widely. This manuscript reviews common types of organic-promoted oxidation reactions and their mechanisms, so as to improve the chemical oxidation technology and put forward some plausible advice.