Abstract: A field experiment was carried out to study effects of four kinds of organic-inorganic mixed fertilizer i.e. canola cake compost （I）,swine manure compost （Ⅱ）,Chinese medicinal herb residue compost （Ⅲ）,and chicken manure compost （IV）,mixed with chemical fertilizer,separately,but equal in N rate on soil nitrogen supply and growth of maize. Results show that during the growing season of the maize,the contents of soil mineral nitrogen with application of organic-inorganic mixed fertilizers were all significantly higher than that in CK （chemical fertilizer alone）,especially in Treatment I and Treatment Ⅱ. The grain yield of maize in the four treatments ranged from 6 725 to 8 960 kg·hm^-2,all higher than CK,while the yields of Treatment Ⅰ,Ⅲ and Ⅳ are more than 20% higher than that of CK,the difference reached to significant level. Nitrogen use efficiency （NUE） of the four treatments varied in the range of 24.2%³9.8%,higher than that of CK. In conclusion,organic-inorganic mixed fertilizer,especially Treatment IV,could efficiently regulate release of N nutrient,keeping soil N supply in coincidence with N demand of maize,and thus significantly increased grain yield of the maize.