Abstract: Effects of exposure to low concentrations(0.005、0.05、0.5 μg·L^-1) of lindane on body length,body weight,hepaticosomatic index(HSI),gonadosomatic index(GSI),spawning and fertilization of zebrafish were studied.Results show that after 14 days of exposure,zebrafish in all the treatments did not have much difference from those in the controls(without lindane and just with solvent) in body length and body weight.But in Treatment 0.5 μg·L^-1,the HSI of both male and female zebrafish increased significantly(P<0.05) and only the GSI of male zebrafish decreased significantly(P<0.05),while no obvious changes in the two indices were found in the other treatments.Compared with what was found in the two controls,lindane remarkably inhibited zebrafish reproduction behavior and reduced spawning and fertilization rate,particularly in Treatments 0.05 and 0.5 μg·L^-1(P<0.01).The findings demonstrate that lindane in the environment is an endocrine disruptor that inhibits to a certain extent the growth and reproduction of zebrafish at low concentration.